Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1998-11-17
1999-12-14
Saucier, Sandra E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424401, 514783, A61K 700
Patent
active
060013672
DESCRIPTION:
BRIEF SUMMARY
The present invention relates to an anti-wrinkle composition containing a polymer system comprising at least one polymer of natural origin, and to the use of this polymer system as a tensioning agent in a cosmetic composition or for the manufacture of a dermatological composition, which are intended in particular for the treatment, reduction, elimination and/or smoothing-out of wrinkles and fine lines on human skin.
In the course of the ageing process, different signs appear on the skin, which are very characteristic of this ageing, reflected in particular by a change in the skin's structure and functions. The main clinical signs of ageing of the skin are, in particular, the appearance of fine lines and deep wrinkles, which increase with age. Disorganization of the skin's "grain" is observed in particular, i.e. the microrelief is less uniform and has an anisotropic nature.
It is known to treat these signs of ageing using cosmetic or dermatological compositions containing active agents that are capable of combating ageing, such as .alpha.-hydroxy acids, .beta.-hydroxy acids and retinoids. These active agents act on wrinkles by removing the dead cells from the skin and by accelerating the process of cell renewal. However, these active agents have the drawback of being effective for the treatment of wrinkles only after they have been applied for a certain period. Now, it is increasingly sought to obtain an immediate effect with the active agents used, leading rapidly to a smoothing-out of wrinkles and fine lines and the disappearance of fatigue marks.
The subject of the present invention is, precisely, the use of a specific polymer system which makes it possible to obtain this effect immediately.
The Applicant has discovered that certain polymers of natural origin have defined physical characteristics and constitute particularly effective tensioning agents. The term "tensioning agent" is understood to refer to compounds capable of having a tensioning effect, i.e. capable of stretching the skin and, by means of this tensioning effect, making the skin smooth and immediately reducing the wrinkles and fine lines on it, or even making them disappear altogether.
In order to be effective, the polymers used according to the invention must have well defined characteristics, and in particular must have a molecular weight of greater than 670,000 daltons, which means that at least a fraction of the polymer has a molecular weight of greater than 670,000 daltons. Moreover, the polymer systems used according to the invention must be capable of forming a steam-permeable film, they must have a Young's modulus ranging from 10.sup.8 to 9.times.10.sup.9 N/m.sup.2 and they must produce, at a concentration of 7% in water, a greater than 1.5% retraction of isolated stratum corneum at 30.degree. C. and at a relative humidity of 40%.
Thus, the subject of the present invention is the use of at least one dispersion of a polymer system containing at least one polymer of natural origin having a molecular weight of greater than 670,000 daltons, the said polymer system being capable of forming a steam-permeable film, having a Young's modulus ranging from 10.sup.8 to 9.times.10.sup.9 N/m.sup.2 and producing, at a concentration of 7% in water, a greater than 1.5% retraction of isolated stratum corneum at 30.degree. C. and at a relative humidity of 40%, in a cosmetic composition for reducing and/or eliminating wrinkles and/or fine lines on the skin by means of a tensioning effect.
The subject of the present invention is also the use of at least one dispersion of a polymer system containing at least one polymer of natural origin having a molecular weight of greater than 670,000 daltons, the said polymer system being capable of forming a steam-permeable film, having a Young's modulus ranging from 10.sup.8 to 9.times.10.sup.9 N/m.sup.2 and producing, at a concentration of 7% in water, a greater than 1.5% retraction of isolated stratum corneum at 30.degree. C. and at a relative humidity of 40%, as a tensioning agent in a cosmetic composition in o
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Bazin Roland
Bernardet Laurent
Candau Didier
Garson Jean-Claude
Malle Gerard
"L'Oreal"
Afremova Vera
Saucier Sandra E.
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