Rice dextrin oral rehydration solution

Details Rice dextrin oral rehydration solution Rice dextrin oral rehydration solution

1993-06-03

1999-01-05

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514867, 536103, A61K 31715, A61K 4740

Patent

active

RE0360325

ABSTRACT:
An improved oral rehydration solution comprising a mixture of rice dextrin and required electrolytes is provided. The functionality of the rice dextrin in oral rehydration solutions is superior to glucose in infants with chronic diarrhea, resulting in lower stool output and enhanced water retention during the initial six hours of therapy. Rice dextrin also has a polymer profile which provides more readily available glucose than corn dextrin or rice flour. There is also provided a process for clarifying solutions of rice dextrin which involves a first filtration at 35.degree. C. and 50.degree. C. and a second filtration at temperatures above 80.degree. C. using filter aid and activated carbon.

REFERENCES:
patent: 4756912 (1988-07-01), Mitchell et al.
patent: 4830861 (1989-05-01), Puski et al.
patent: 4876096 (1989-10-01), Mitchell et al.
patent: 4942042 (1990-07-01), Bhargava et al.
Patra et al. Archives of Disease in Childbood, 57:910-912 (1982).
Molla et al. The Lancet, 1317-1319 (1982).
El Mougi et al. J. of Pediatric Gastroenterology and Nutrition, 7:572-576 (1988).
Molla et al. J. of Pediatric Gastroenterology and Nutrition, 8:81-84 (1989).
Mauer et al., "Use of Oral Fluid Therapy and Posttreatment Feeding Following Enteritis in Children in a Developed Country", Committee on Nutrition, Pediatrics, vol. 75, No. 2, Feb. 1985.
Lebenthal et al., J. Pediatrics, 103:29-34 (1983).
Carpenter et al., New England Journal of Medicine, 319:1346-1348 (1988).
Daum et al., Pediatr. Res., 12: 24-26, 1978, "Intestinal Osmolality and Carbohydrate Absorption in Rats Treated with Polymerized Glucose".
Klish et al., Pediatr. Res., 14 1343-1346, 1980, "The Effect of Intestinal Solute Load on Water Secretion in Infants with Acquired Monosaccharide Intolerance".
Sandhu et al., 57, 152-160, 1982, "Oral rehydration in acute infantile diarrhoea with a glucose-polymer electrolyte solution".
Mahalanabis et al., J. Diar. Dis. Res. 1(2):76-81, Jun. 1983, "In Search of a Super Oral Rehydration Solution: Can Optimum Use of Organic Solute-Mediated Sodium Absorption Lead To The Development Of An Absorption Promoting Drug?".
Lehringer, Albert L. Biochemistry: The Molecular Basis of Cell Structure and Function. Woth Publishers: New York, 1975, pp. 62-63.

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