Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-05-25
1995-01-10
Rotman, Alan L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546327, 502213, C07D21379, C07D21381, C07D21382, B01J 27185
Patent
active
053808614
ABSTRACT:
It has been found that pyridine-2-carboxamides of the formula ##STR1## wherein R is amino or a residue convertible into amino, and pharmaceutically usable acid addition salts of that carboxamide in which R is amino can be prepared in a simple manner and in good yield by reacting 2,5-dichloropyridine in the presence of a palladium-phosphine catalyst with an alkyne of the formula
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Scalone Michelangelo
Vogt Peter
Ciambrone Coletti Ellen
Gould George M.
Hoffmann-La Roche Inc.
Johnston George W.
Rotman Alan L.
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