Preparation of azetidinones via novel protected intermediates

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Other Related Categories

C07D20508, C07B 5100, C07B 3710

Type

Patent

Status

active

Patent number

049636707

Description

ABSTRACT:
A multistep process is disclosed for preparing azetidinone intermediates used in the making penems and carbapenems wherein intermediates containing ##STR1## R' is independently hydrogen or 1, 2 or 3 of lower alkyl or lower alkoxy, preferably hydrogen, wherein R" is methyl, ethyl, a phenyl or alkyl, preferably ethyl, as a readily removable nitrogen protecting group are made.

REFERENCES:
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Chemical Abstracts 103, No. 19, Abstract 160299c (1985).
Chemical Abstracts 102, No. 17, Abstract 149103t (1985).
Sundberg et al., J. Org. Chem. 38 3324 (1973).
Shiozaki, Tet. Letters 22, 5205 (1981).

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