Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-06-18
1999-08-03
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514255, 544231, 544349, 544385, A61K 31495, C07D24136, C07D24104, C07D23700
Patent
active
059325798
ABSTRACT:
Novel inhibitors of metalloproteases, in particular collagenase-1 and stromelysin-1, are disclosed. Such compounds are useful in pharmaceutical compositions and methods for treating or controlling disease states or conditions which involve tissue breakdown, such as rheumatoid arthritis. ##STR1##
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Campbell David
Look Gary C.
Patel Dinesh V.
Szardenings Anna Katrin
Affymax Technologies N.V.
Kifle Bruck
Shah Mukund J.
Stevens Lauren L.
Swiss Gerald F.
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