Peptides which inhibit adhesion between leukocytes and endotheli

Details Peptides which inhibit adhesion between leukocytes and endotheli Peptides which inhibit adhesion between leukocytes and endotheli

1994-11-30

1999-08-03

Caputa, Anthony C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241901, 4242341, 4242401, 4242531, 530300, 530350, A61K 3900, A61K 3902, A61K 3910, A61K 3800

Patent

active

059322179

ABSTRACT:
Peptides which will inhibit the reaction between the RGD tripeptide of FHA and the integrin receptors of endothelial cells and their utility as therapeutic agents are described.

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Graf et al., 1987, Biochemistry--26: 6896-6900.
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Tuomanen et al., 1989, J. Exp. Med. 170:959-69.
Tuomanen et al., 1988, J. Exp. Med. 168:267-77.
Tuomanen and Weiss, 1985, J. Infect. Dis. 152:118-25.
Tuomanen et al., 1985, J. Infect. Dis. 151:859-68.

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