Nifedipine isosorbide 5-monoitrate combination product

Details Nifedipine isosorbide 5-monoitrate combination product Nifedipine isosorbide 5-monoitrate combination product

1987-09-18

1988-06-07

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514470, A61K 3134, A61K 3144

Patent

active

047497149

ABSTRACT:
A solid medicament formulation which can be administered orally comprising 5 to 30 mg of nifedipine and 10 to 40 mg of isosorbide 5-mononitrate. Oral administration of such cardioactive formulation reduces the time tolerance to the isosorbide 5-mononitrate alone.

REFERENCES:
The Merck Index (1983) p. 751.
Table; article of U. Borchard et al. in Med. Klin. 1985, pp. 21-23.

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