Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1984-04-26
1988-06-07
Shippen, Michael L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 28, 514 32, 514 36, 514 38, 514 39, 514 41, 514200, 514201, 514202, 514203, 514204, 514206, 514208, 514551, A61K 31545
Patent
active
047496940
ABSTRACT:
Novel lysine esters used as absorption enhancing agents for gastrointestinally and rectally administered drugs. Also provided are processes for preparation of said lysine ester compounds as well as pharmaceutical formulations and methods for their use as absorption enhancing agents.
REFERENCES:
patent: 3433779 (1959-03-01), Vogler
patent: 4154956 (1979-05-01), Ueda
patent: 4296095 (1981-10-01), Hoppe
Roche, "Design of Biopharmaceutical Properties Through Prodrugs and Analogs," pp. 281-315 (1977).
Fix Joseph A.
Pogany Stefano A.
Merck & Co. , Inc.
Polk Manfred
Shippen Michael L.
Sudol Michael C.
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