Tetrazole derivatives, having a further unsaturated heterocyclic

Details Tetrazole derivatives, having a further unsaturated heterocyclic Tetrazole derivatives, having a further unsaturated heterocyclic

1986-05-30

1988-08-23

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514252, 514256, 514326, 514340, 514365, 514372, 514374, 514381, 514382, 5142288, 5142362, 546210, 546276, 544 56, 544 98, 544132, 544333, 544366, 544405, 548200, 548236, 548239, 548248, 548251, 548252, C07D25704, C07D41306, A61K 3141, A61K 31535

Patent

active

047661208

ABSTRACT:
Tetrazole derivatives of the formula: ##STR1## wherein R.sup.1 is an optional defined substituent; A is sulfur or a lower alkylene-thio, l is 0 or 1; B is a lower alkylene; R.sup.2 is hydroxy, a lower alkoxy, or a group: ##STR2## wherein R.sup.3 and R.sup.4 are optional defined substituents, or the R.sup.3 or R.sup.4 may combine together with the nitrogen atom to which they are joined to form a defined heterocyclic group, and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and also anti-inflammatory activity and are useful as an anti-ulcer or anti-inflammatory drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical compositon containing said tetrazole derivatives.

REFERENCES:
patent: 3372953 (1983-02-01), Uchida et al.
patent: 4540703 (1985-09-01), Uchida et al.
patent: 4663323 (1987-05-01), Uchida et al.

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