Tetrazole ureas and thioureas and their use as ACAT inhibitors

Details Tetrazole ureas and thioureas and their use as ACAT inhibitors Tetrazole ureas and thioureas and their use as ACAT inhibitors

1990-04-27

1991-12-17

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548251, C07D25706, A61K 3141

Patent

active

050735659

ABSTRACT:
Novel ACAT inhibitors useful in the treatment of atherosclerosis which are N-aryl-N'-tetrazole ureas and thioureas.

REFERENCES:
Chem. Abst. 76:25184v (1972).
J. Med. Chem. 22:28-32 (1979).
Berge, et al., J. Pharm. Sciences, 66:1-19 (1977).
Field, et al., Biochem. et Biophys., 712:557-570 (1982).

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