Human tissue plasminogen activator

Details Human tissue plasminogen activator Human tissue plasminogen activator

1983-04-07

1988-08-23

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351723, 435212, 435215, 435253, 435320, 536 27, 935 14, 935 29, 935 32, 935 70, 935 73, C12N 500, C12N 1500, C12N 948, C12N 972, C12N 120, C12N 100, C07H 1700

Patent

active

047660759

ABSTRACT:
Human tissue phasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.

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