Cis-4,5-didehydro-cis-13-PGE.sub.1 , compounds

Details Cis-4,5-didehydro-cis-13-PGE.sub.1 , compounds Cis-4,5-didehydro-cis-13-PGE.sub.1 , compounds

1977-03-03

1978-12-12

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260410, 2604105, 2604109R, 260413, 560121, 562503, C07C17700

Patent

active

041295820

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is of the cis configuration. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 3932479 (1976-01-01), Bernady et al.

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