Substituted .beta.-amino acid derivatives useful as platelet agg

Details Substituted .beta.-amino acid derivatives useful as platelet agg Substituted .beta.-amino acid derivatives useful as platelet agg

1992-04-10

1993-08-24

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 13, 560 35, 562430, C07C25124, C07C25718

Patent

active

052391132

ABSTRACT:
Novel substituted .beta. amino acid derivatives are provided which inhibit platelet aggregation and intermediates thereof. This invention also pertains to pharmaceutical compositions and methods of using such derivatives.

REFERENCES:
patent: 3862228 (1975-01-01), Rodriguez et al.
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4661111 (1987-04-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4857508 (1989-08-01), Adams et al.
patent: 4879313 (1989-11-01), Tjoeng et al.
patent: 5053393 (1991-10-01), Tjoeng et al.
patent: 5084466 (1992-01-01), Alig et al.
Koczewiak et al., Biochem. 23, 1767-1774 (1984).
Plow et al., Proc. Natl. Adac. Sci. 82, 8057-8061 (1985).
Ruggeri et al., Proc. Natl. Acad. Sci. 83, 5708-5712 (1986).
Haverstick et al., Blood 66 (4) 948-952 (1985).
Ruoslahti an Pierschbacher, Science 238, 491-497 (1987).
R. T. Boere et al, J. Organomet. Chem. 331, 161-167 (1987).
W. E. Parham, C. K. Bradsher, Acct. Chem. Res. 300 (1982).
M. Taddei and A. Ricci, Synthesis 633-635 (1986).
Ginsberg et al, J. Biol. Chem. 260 (7), 3931-3936 (1985).
C. F. Allen and J. W. Gates, Org. Synth. Coll. vol. 3 140 (1955).

Affiliated with

Also associated with

Rating

Substituted .beta.-amino acid derivatives useful as platelet agg does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted .beta.-amino acid derivatives useful as platelet agg, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted .beta.-amino acid derivatives useful as platelet agg will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-830595