Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidin

Details Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidin Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidin

1984-04-02

1985-06-04

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514412, 546 17, 546216, 546221, 546208, 548409, C07D491113, A61K 31455

Patent

active

045215375

ABSTRACT:
Spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine and -3'-pyrrolidine] compounds of the formula ##STR1## where the substituents are as defined herein, are useful in the treatment of hypertension in mammals. Such compounds, their use as antihypertensive agents, pharmaceutical compositions containing the compounds, intermediates and processes for preparing the compounds are provided.

REFERENCES:
patent: 3679666 (1972-07-01), Maiatestinic et al.
patent: 4405631 (1983-09-01), Kosley et al.

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