Fluoroalkyl/alkenyl-substituted benzoylguanidines, process for t

Details Fluoroalkyl/alkenyl-substituted benzoylguanidines, process for t Fluoroalkyl/alkenyl-substituted benzoylguanidines, process for t

1998-02-24

1999-12-07

Clardy, S. Mark

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514618, 514619, 564142, 564161, 564230, 564237, 564182, 546139, 546141, 546152, 546153, 546290, A61K 31165, C07C23100, C07C27700, C07C27900

Patent

active

059984813

ABSTRACT:
There are described benzoylguanidines of the formula I ##STR1## having the definitions of R(1) to R(4) indicated in the text, and their pharmaceutically tolerable salts. They are obtained by reaction of a compound II ##STR2## with guanidine. They are outstanding agents for the treatment of disorders of the cardiovascular system.

REFERENCES:
patent: 3780027 (1973-12-01), Cragoe, Jr. et al.
patent: 5091394 (1992-02-01), Englert et al.
patent: 5373024 (1994-12-01), Lang et al.
Derwent Abstract of EP 602 522, 1994.
Derwent Abstract of EP 604 852, 1994.

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