Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1983-12-27
1988-04-26
Tarcza, John Edward
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351723, 435 70, 4352402, 935 32, 935 56, 935 33, 935 70, C12P 2100, C12P 2102, C12N 1500, C12N 0500
Patent
active
047404612
ABSTRACT:
Eucaryotic cells cotransformed with product and selection genes yield considerably greater quantities of product after a novel subcloning strategy is employed: Transformants are identified for product yield, cultured under selection pressure and the progeny screened for product yield. Novel transformation vectors contain directly ligated selection and product genes and/or eucaryotic promoters.
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Bak Mary E.
Berstein David L.
Eisen Bruce M.
Genetics Institute Inc.
Tarcza John Edward
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