Substituted cinnamic acid guanidides, a process for their prepar

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514351, 514522, 514620, 514622, 514634, 514821, 514824, 514921, 546306, 558414, 564134, 564139, 564163, 564165, 564237, A61K 3144, A61K 31275, A61K 31155

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058831339

ABSTRACT:
Compounds of the formula I ##STR1## are described in which at least one of the substituents R(1), R(2), R(3), R(4) and R(5) is a nitrogen-containing heterocyclic radical. They are outstanding cardiovascular therapeutic agents. They are obtained by reaction of a compound II ##STR2## with guanidine.

REFERENCES:
patent: 2734904 (1956-02-01), Burtner et al.
patent: 5364868 (1994-11-01), Englert et al.

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