Substituted tetrahydrobenzothiazoles as dopaminergic agents

Details Substituted tetrahydrobenzothiazoles as dopaminergic agents Substituted tetrahydrobenzothiazoles as dopaminergic agents

1989-03-14

1991-01-29

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514253, 544360, 544364, A61K 31495, C07D41714

Patent

active

049886991

ABSTRACT:
Substituted tetrahydrobenzothiazoles are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as dopamine agonists with selectivity for the presynaptic dopamine receptor and are useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.

REFERENCES:
patent: 3944551 (1976-03-01), Regnier
patent: 4260610 (1981-04-01), Regnier
patent: 4308266 (1981-12-01), Seiler
patent: 4613601 (1986-09-01), Regnier
patent: 4731374 (1988-03-01), Griss

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