N-acyl-N-napthoylglycines as aldose reductase inhibitors

Details N-acyl-N-napthoylglycines as aldose reductase inhibitors N-acyl-N-napthoylglycines as aldose reductase inhibitors

1987-12-23

1989-06-27

Gray, Bruce D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514212, 514479, 514481, 514562, 514563, 514604, 514635, 560 10, 560 28, 560 39, 560 41, 562427, 562439, 562444, 562449, 562450, A61K 3726

Patent

active

048430625

ABSTRACT:
Disclosed herein are N-acyl-N-napthoylglycines and methods of their preparation. The N-acyl-N-napthoylglycines are novel aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

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Y. Mitin et al, Izv. Akad. Nauk SSR, Ser. Khim., 11, 2666 (1968), CA 70: 68721m.
A. Bates et al, Helv. Chim. Acta, 58 (3), 688 (1975).

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