Tetrahydropyrido[3',4':4,5]pyrrolo[2,3-c]quinolines and their us

Details Tetrahydropyrido[3',4':4,5]pyrrolo[2,3-c]quinolines and their us Tetrahydropyrido[3',4':4,5]pyrrolo[2,3-c]quinolines and their us

1987-02-05

1988-09-13

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 64, 546162, A61K 3147, C07D47114

Patent

active

047710527

ABSTRACT:
There are disclosed compounds of the formula ##STR1## where X and Y are independently hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, trifluoromethyl or nitro; R.sub.1 is hydrogen or loweralkyl; R.sub.2 is hydrogen, loweralkyl, loweralkylcarbonyl or arylcarbonyl; and R.sub.3 is hydrogen, loweralkyl, arylloweralkyl, ##STR2## loweralkylcarbonyl or arylcarbonyl, n being an interger of 1 to 6 inclusive and Z being hydrogen, loweralkyl, loweralkoxy, hydroxy or halogen; which are useful as hypotensive agents.

REFERENCES:
Beveridge et al., Aust. J. Chem., 25, 1341 (1972).
Khan et al., J. Het. Chem., 15, 913 (1978).
Wing et al., Chem. Abstracts, vol. 82 (1975), entry 97970v.
Burger, ed., Medicinal Chemistry, 2nd ed., Interscience (1960) pp. 42-43.

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