Flavin adenine dinucleotide-iodothyronine conjugates

Details Flavin adenine dinucleotide-iodothyronine conjugates Flavin adenine dinucleotide-iodothyronine conjugates

1978-06-22

1979-10-16

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 7, 536 24, 536 27, 536 28, C07H 1916

Patent

active

041714326

ABSTRACT:
Conjugates of the formula: ##STR1## wherein Riboflavin-(Phos).sub.2 -Ribose represents the riboflavin-pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), n equals 2 through 6, Y is hydrogen or trifluoroacetyl, and .beta..sup.1 and .beta..sup.2 are, independently, hydrogen or iodine; and intermediates in the synthesis of such FAD conjugates. The FAD-iodothyronine conjugates, particularly where the iodothyronine is thyroxine, are useful as labeled conjugates in specific binding assays for determining the iodothyronine in liquid media such as serum.

REFERENCES:
patent: 3590029 (1971-06-01), Koch
patent: 3983104 (1976-09-01), Vorbruggen
patent: 4040907 (1977-08-01), Ullman et al.
patent: 4043872 (1977-08-01), Blakemore et al.

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