Viral antibody diagnostic test system

Details Viral antibody diagnostic test system Viral antibody diagnostic test system

1978-09-27

1979-11-27

Fagelson, Anna P.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, 424 13, 424 86, 424 89, 422 55, 422 68, G01N 3100, G01N 3114, G01N 3316

Patent

active

041761740

ABSTRACT:
A diagnostic reagent for detecting the presence of specific microbial antibodies in body fluids which comprises a gel containing intact erythrocytes, which have appropriate microbial particles adhering directly or indirectly to the surface thereof, the gel being contained in a shallow vessel. The system may additionally include complement, or alternatively this may be added separately and after test-body fluids have been applied to the gel. Interaction of specific antibodies with the microbial particles, in the presence of complement results in the lysis of the erythrocytes thereby forming a visible positive result.

REFERENCES:
patent: 3715427 (1973-02-01), Hirata
patent: 3843777 (1974-10-01), Hainski
Milgrom, Vox Sang., vol. 8, 1963, pp. 537-548.
Jackson, Applied Microbiol., vol. 27, 1974, pp. 896-900.
Baker, Applied Microbiol., vol. 17, 1969, pp. 422-426.
Dubois, Arch. fuer Exper. Vet. Med., vol. 24, 1970, pp. 33-59.
Kwapinski, Meth. of Immunochem. & Immunol. Res., Wiley-Intersci., N.Y. 1972, pp. 397-408, 441-464, 545-547.
Fazekas, Australian J. Exptl. Biol. Med., vol. 27, 1949, pp. 65-81.
Russell, J. Gen. Virol. vol. 27, No. 1, Apr. 1975, pp. 1-10.
Schild et al., Symp. Series Immunobiol. Standards, vol. 20, 1972, pp. 39-46.

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