Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-03-03
1994-07-05
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483041, 424 2, 424 9, C07D49504, A61K 31415
Patent
active
053267788
ABSTRACT:
The present invention provides compounds which are covalent conjugates of deferoxamine and biotin or derivatives thereof. The subject compounds are capable of binding metal ions and avidin or streptavidin, and accordingly are useful in two-step radioimmunoimaging and radioimmunotherapy. Methods for the synthesis of the deferoxamine-biotin conjugates are also provided by the present invention.
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Brust Joseph Paul
Gabilan Mary Susan H.
Research Corporation Technologies Inc.
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