Process for the production of 2-acetamidocinnamic acid

Details Process for the production of 2-acetamidocinnamic acid Process for the production of 2-acetamidocinnamic acid

1978-12-13

1981-03-03

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

560142, 562450, C07D31744, C07C10142

Patent

active

042540356

ABSTRACT:
2-acetamidocinnamic acid and substituted 2-acetamidocinnamic acids are prepared by reacting glycine with an aromtic aldehyde in the presence of acetic anhydride and a tertiary amine and subsequently treating with water.

REFERENCES:
patent: 3347928 (1967-10-01), Taub et al.
patent: 3878043 (1975-04-01), Matta et al.
patent: 4124533 (1978-11-01), Knowles et al.
Org. Synth., Col, vol. 2 (1963), pp. 1-3. _
Dakin, J. Biol. Chem., vol. 82 (1929), pp. 439-446. _
Bergmann et al., Justus Liebigs Ann. Chem., vol. 448 (1926), pp. 20-31. _

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