Process for producing 2-alkyl-4-halo-5-formylimidazoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D23364

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active

053190947

ABSTRACT:
This invention provides a process for producing 2-alkyl-4-halo-5-formylimidazoles which includes halogenating 2-alkyl-5-formylimidazoles with a N-halosuccinimides in the presence of dioxane or mixture of dioxane and ethylene glycol monomethylether as solvent and in the presence of alkali metal hydrogen carbonate as catalyst, which are readily available, with good yield.

REFERENCES:
patent: 4207324 (1980-06-01), Matsumura et al.
patent: 4810828 (1989-03-01), Fenske et al.
patent: 4995898 (1991-02-01), Nasu et al.
patent: 5023336 (1991-06-01), Shigehara et al.

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