Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H

Details Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H

1982-11-12

1984-09-18

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 5, 546 94, 546165, 546167, 546171, A01N 4350, A61K 3147, C07D45504

Patent

active

044724063

ABSTRACT:
Certain 6,7-dihydro-8-(imidazol-1-yl)-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxyli c acids are disclosed as potent antimicrobial agents with an unusual spectrum of activity. Esters, acyl chlorides, alkylaminoalkyl ester salts, salts of a nitrogen atom of the imidazole ring, and pharmaceutically acceptable carboxylate salts are also disclosed. Novel synthetic intermediates are also described.

REFERENCES:
patent: 3896131 (1975-07-01), Gerster
patent: 4404207 (1983-09-01), Stern
Abstract of Japanese Patent Application 106,776 (published Dec. 16, 1980).
Abstract for Japanese Laid-Open Application No. 57-88183 (published Nov. 21, 1980).

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