5-heteroarylamino-6-oxy-substituted 3(2H)-pyridazinones

Details 5-heteroarylamino-6-oxy-substituted 3(2H)-pyridazinones 5-heteroarylamino-6-oxy-substituted 3(2H)-pyridazinones

1992-12-21

1994-06-07

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514252, 514253, 544115, 544238, A61K 3150

Patent

active

053189680

ABSTRACT:
A compound of the formula, ##STR1## or its pharmaceutically acceptable salt, and its preparation process and pharmaceutical compositions characterized by containing these compounds as effective ingredients.
These compounds have strong antithrombotic activity, cardiotonic activity, vasodilator activity and anti-SRS-A activity, and are useful as prophylactic or therapeutic agents for various thrombotic affections, congestive heart failure, hypertension, asthma, immediate type allergy diseases and the like.

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Burger, ed "Medicinal Chemistry" 2nd Edition Interscience, N.Y. (1960) p. 42.
K. Buler and D. Pearson "Organic Synthesis", Moscow, MIR Publishers, 1973, vol. 2, pp. 433-434 (Fragment).
Ferluy, Chem Abstr vol. 77 entry 68522v.
Galoyan et al. Chem. Abstr vol. 75 entry 140758b (1971).

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