Human glutamate-binding protein

Details Human glutamate-binding protein Human glutamate-binding protein

1996-11-14

1999-09-21

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 912, 4352402, 4352523, 4353201, 536 231, 536 2432, 536 234, 530350, 935 1, 935 19, 935 52, C12N 1500, C12N 1512, C12N 1511, C07K 1400

Patent

active

059553014

ABSTRACT:
The present invention provides a human glutamate-binding protein (HGLUBP) and polynucleotides which identify and encode HGLUBP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HGLUBP and a method for producing HGLUBP. The invention also provides for use of HGLUBP and agonists, antibodies, or antagonists specifically binding HGLUBP, in the prevention and treatment of diseases associated with expression of HGLUBP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HGLUBP for the treatment of diseases associated with the expression of HGLUBP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HGLUBP.

REFERENCES:
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