Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-05-24
1996-12-03
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 435 912, 536 243, 536 2432, C12Q 168, C12Q 170, C12P 1934, C07H 2104
Patent
active
055807186
ABSTRACT:
Oligonucleotides primers can be used to amplify and detect Hepatitis C virus nucleic acids in a process that involves reverse transcription of the viral genomic RNA to create cDNA and the subsequent amplification of the cDNA by the polymerase chain reaction. Oligonucleotide probes can be used to detect the presence of amplified DNA by hybridization. The invention provides improved methods, compositions, and kits for amplifying and detecting U.S., Japan, and HCV-C prototype nucleic acids.
REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4965188 (1990-10-01), Gelfand et al.
Saiki et al., 1988, "Diagnosis of Sickle Cell Anemia and B-Thalassemia With Enzymatically Amplified DNA and Nonradioactive Allele-Specific Oligonucleotide Probes"N. Eng. J. Med. 319(9):537.541.
Choo et al., 1989, "Isolation of a cDNA Clone Derived From a Blood-Borne Non-A, Non-B viral Hepatitis Genome" Science 244:359-362.
Choo et al., 1991, "Genetic Organization and Diversity of the Hepatitis C Virus" Proc. Natl. Acad. Sci. USA 88:2451-2455.
Kato et al., 1990, "Molecular Cloning of the Human Hepatitis C Virus Genome From Japanese Patients With Non-A, Non-B Hepatitis" Proc. Natl. Acad. Sci. USA 87:9524-9528.
Takamizawa et al., 1991, "Structure and Organization of the Hepatitis C Virus Genome Isolated From Human Carriers" J. Virol. 65(3):1105-1113.
Takeuchi et al., 1990, "Nucleotide Sequence of Core and Envelope Genes of the Hepatitis C Virus Genome Derived Directly From Human Healthy Carriers" Nuc. Acids Res. 18(15):4626.
Maeno et al., 1990, "A cDNA Clone Closely Associated With Non-A, Non-B Hepatitis" Nuc. Acids Res. 18(9):2685-2689.
Okamoto et al., 1991, "Nucleotide Sequence of the Genomic RNA of Hepatitis C Virus Isolated From a Human Carrier: Comparison With Reported Isolates for Conserve and . . . Regions" J. General Virology 72:2697-2704.
Clewley, 1990, "Detection of Hepatitis C Virus RNA in Serum" Lancet 336:309-310.
Enomoto et al., 1990, "There are Two Major Types of Hepatitis C Virus in Japan" biochem. Biophys. Res. Commun. 170(3):1021-1025.
Garson et al., 1990, "Detection of Hepatitis C Viral Sequences in Blood Donations by `Nested` Polymerase Chain Reaction and Prediction of Infectivity" Lancet 335:1419-1422.
Garson et al., 1990, "Demonstration of Viraemia Patterns in Haemophiliacs Treated With Hepatitis-C-Virus-Contaminated Factor VIII Concentrations" Lancet 336:1022-1025.
Kaneko et al., 1990, "Detection of Serum Hepatitis C Virus RNA" Lancet 335:976.
Kato et al., 1990, "Detection of Hepatitis C Virus Ribonucleic Acid in the Serum by Amplification With Polymerase Chain Reaction" J. Clin. Invest. 86;1764-1767.
Kato et al., 1990, "Sequence Diversity of Hepatitis C Viral Genomes" Mol. Biol. Med. 7:495-501.
Kubo et al., 1989, "A cDNA Fragment of Hepatitis C Virus Isolated From an Implicated Donor of Post-Transfusion Non-A, Non-B Hepatitis in Japan" Nuc. Acids Res. 17(24):10367-10372.
Ohkoshi et al., 1990, "Detection of Hepatitis C Virus RNA in Sera and Liver Tissues of Non-A, Non-B Hepatitis Patients Using the Polymerase Chain Reaction" Jpn. J. Cancer Res. 81:862-865.
Shimizu et al., 1990, "Early Events in Hepatitis C Virus Infection of Chimpanzees" Proc. Natl. Acad. Sci. USA 87:6441-6444.
Simmonds et al., 1990, "Hepatitis C Quantification and Sequencing in Blood Products, Haemophiliacs, and Drug Users" Lancet 336:1469-1472.
Takeuchi et al., 1990, "Hepatitis C Viral cDNA Clones Isolated From a Healthy Carrier Donor Implicated in Post-Transfusion Non-A, Non-B Hepatitis" Gene 91:287-291.
Ulrich et al., 1990, "Detection, Semiquantitation, and Genetic Variation in Hepatitis C Virus Sequences Amplified From the Plasma of Blood Donors With Elevated Alanine Aminotransferase" J. Clin. Invest. 86:1609-1614.
Weiner et al., 1990, "Detection of Hepatitis C Viral Sequences in Non-A, Non-B Hepatitis" 335:1-3 Lancet.
Yoneyama et al., 1990, "Detection of Hepatitis C Virus cDNA Sequence by the Polymerase Chain Reaction in Hepatocellular Carcinoma Tissues" Jpn. J. Med. Sci. Biol. 43:89-94.
Zonaro et al., 1991, "Detection of Serum Hepatitis C Virus RNA in Acute Non-A, Non-B Hepatitis" J. Infect. Diseases 163:923-924.
Takeuchi et al., 1990, "The Putative Nucleocapsid and Envelope Protein Genes of Hepatitis C Virus Determined by Comparison of the Nucleotide Sequences of Two Isolates Derived From an Experimentally Infected Chimpanzee and Healthy Human Carriers" J. Gen. Vir. 71:3027-3033.
Okamoto et al., 1990, "The 5'-Terminal Sequence of the Hepatitis C Virus Genome" Japan J. Exp. Med. 60(3):167-177.
Han et al., 1991, "Characterization of the Terminal Regions of Hepatitis C Viral RNA: Identification of Conserved Sequences in the 5'-Untranslated Region of Poly(A) Tails at the 3'End" Proc. Natl. Acad. Sci. USA 88:1711-1715.
Okamoto et al., 1990, "Detection of Hepatitis C Virus RNA by a Two-Stage Polymerase Chain Reaction With Two Pairs of Primers Deduced From the 5'-Noncoding Region" Japan J. Exp. Med. 60(4):215-222.
Kanai et al., 1990, "Suppression of Hepatitis C Virus RNA by Interferon-Alpha" Lancet 336:245.
Garson et al., 1990, "Enhanced Detection by PCR of Hepatitis C Virus RNA" Lancet 336:878-879.
Lee et al., 1992, J. Clin. Microbiology 30(6):1602-1604 "Identification of Hepatitis C Viruses With a Nonconserved Sequence of the 5' Untranslated Region".
Bethesda Research Laboratories Catalogue-Reference Guide (published in 1985 by Bethesda Research Laboratories, Gaitherburg, MD) pp. 52 and 53.
Kato et al., 1989, "Japanese Isolates of the Non-A, Non-B Hepatitis Viral Genome Show Sequence Variations from the Original Isolate in the U.S.A." Proc. Japan Acad. 65(9):219-223 (Ser. B).
Sommer et al., 1989, "Minimal Homology Requirements for PCR Primers" Nucleic Acids Res. 17(16):6749.
Matthews et al Analytical Biochemistry 169:1-25, 1988.
Kato et al. PNAS 87:9524-9528, 1990.
Takimazawa et al. J. of Virol. 65:1105-1113.
Enomoto et al. Biochem. Biophys. Res. Comm 170: 1021-1025, 1990.
Resnick Robert M.
Young Karen K. Y.
Gould George M.
Hoffmann-La Roche Inc.
Petry Douglas A.
Rees Dianne
Sias Stacey R.
LandOfFree
Primers and probes for detection of hepatitis C and novel varian does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Primers and probes for detection of hepatitis C and novel varian, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Primers and probes for detection of hepatitis C and novel varian will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-784411