Process for the preparation of acyl isocyanates

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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562871, 549 72, 549487, 558415, C07D21378, C07D30510, C07D33338, C07C26302

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active

049703196

ABSTRACT:
The invention relates to a process for the preparation of acyl isocyanates of formula ##STR1## in which R is an alkyl radical, a substituted or unsubstituted naphthyl or phenyl radical or a substituted or unsubstituted aromatic heterocyclic radical, which consists in reacting an acyl halide of formula ##STR2## in which R has the above meaning and X denotes a fluorine, chlorine or bromine atom, with a sodium or potassium cyanate in the presence of a compound chosen from tin(IV), zinc or nickel(II) halides.
The acyl isocyanates thus prepared are very useful for forming ureas or carbamates.

REFERENCES:
patent: 3155700 (1964-11-01), Steyermark et al.
patent: 3450747 (1969-06-01), Smith et al.
patent: 3850985 (1974-11-01), Hagemann
patent: 4529919 (1985-07-01), Clifford et al.
Anhydrous aluminum Choride in Organic Chemistry, C. A. Thomas, 1941, pp. 156-157, 381, 531, 596, 602, 636-644.
Synthetic Methods of Organic Chemistry, W. Theilheimer, 1972, 26/687, p. 334.
Chemical Communication, H. H. Wasserman and S. H. Wentland, 1969, p. 1216.

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