Sulfonic acid substituted aromatic steroids as inhibitors of ste

Details Sulfonic acid substituted aromatic steroids as inhibitors of ste Sulfonic acid substituted aromatic steroids as inhibitors of ste

1988-12-23

1990-11-13

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514169, 514176, 514177, 514178, 514179, 514182, 540 23, 540 95, 540100, 540508, 540522, 540524, 540525, 540531, 540539, 540540, 540541, 540553, 540554, 552558, A61K 3158, A61K 3156, C07J 100, C07J 7100

Patent

active

049702050

ABSTRACT:
Invented are sulfonic acid substituted analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase, including using these compounds to reduce or maintain prostate size. Also invented are intermediates used in preparing these compounds.

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