Protein from albus albopictus cells and method for its use

Details Protein from albus albopictus cells and method for its use Protein from albus albopictus cells and method for its use

1995-11-16

1998-10-06

Marx, Irene

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 703, 530350, A01N 3748, C07K 100

Patent

active

058176195

ABSTRACT:
The present invention provides a novel isolated and purified protein that is produced by Aedes albopictus L4.4 cells, having a molecular weight of 55 kDa of SDS-PAGE, is associated with lysosomal membranes and induces an anti-viral state. This anti-viral state is characterized by a total block of virus RNA synthesis with no effect of cell macromolecular synthesis. Also provided are various methods of using this novel protein or the gene encoding this protein.

REFERENCES:
patent: 4859464 (1989-08-01), D'Antonio
patent: 5217879 (1993-06-01), Huang et al.
Miller et al (1993) Journal of General Virology, 74, 293-98.
Luo et al (1993) Virology, 194, 44-49.

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