Anticholinergic glucuronide compounds and antiperspirant use the

Details Anticholinergic glucuronide compounds and antiperspirant use the Anticholinergic glucuronide compounds and antiperspirant use the

1983-06-13

1985-05-14

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424DIG5, 424 66, 424 67, 424 68, 424 69, 514770, 514941, 514969, A61K 732, A61K 734, A61K 738, A61K 912

Patent

active

045171769

ABSTRACT:
This invention relates to the preparation and use of glucuronide derivatives of anticholinergic compounds to render them safe for use in the control of human perspiration. These derivatives, which lack mydriatic potency in the eye, are applied to the axillae where they are rendered biologically active by the action of .beta.-glucuronidase occurring naturally on the skin.

REFERENCES:
patent: 3312709 (1967-04-01), MacMillan
patent: 3326768 (1967-06-01), MacMillan
patent: 3527864 (1970-09-01), MacMillan et al.
patent: 3624200 (1971-11-01), Moffett
patent: 3678156 (1972-07-01), MacMillan et al.
patent: 3767786 (1973-10-01), MacMillan
patent: 3775538 (1973-11-01), DeSalva et al.
patent: 3833592 (1974-09-01), Papanastassiou et al.
patent: 3839345 (1974-10-01), Pars et al.
patent: 3953599 (1976-04-01), MacMillan

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