Topical composition containing a substance P antagonist

Details Topical composition containing a substance P antagonist Topical composition containing a substance P antagonist

1998-06-15

1999-10-26

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514210, 514293, 514305, 514315, 514410, 514416, 514422, 514423, 514426, 514438, 514461, 514613, 514617, 514663, 514646, A61K 3800, A61K 31135

Patent

active

059728922

ABSTRACT:
The invention relates to a therapeutic composition for topical application containing at least one product with an irritant side effect and a substance P antagonist for reducing or even eliminating the irritant effect of this product.
It also relates to the use of a substance P antagonist for the preparation of a pharmaceutical composition for topical application containing at least one product with an irritant side effect for reducing or even eliminating the irritant effect of this product.
The substance P antagonist may be a peptide compound or a nitrogen-containing compound or a nitrogen-, sulphur- or oxygen-containing heterocyclic compound.

REFERENCES:
patent: 5569662 (1996-10-01), Satake et al.
Beding-Basrekow et al, Exp. Eye Res., 50(1), 21-26, Jan. 1990.
Anderson et al, Eu.J. Pharmacol 209, 175-183, 1991.
Wallengren, Br. J. Dermatoe., 124, 324-328, 1991.

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