Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-11-23
1997-06-10
Elliott, George C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 4, 435 5, 435 71, 435181, 530402, 568333, C12Q 168, C12Q 170, C07K 100, C07C 4976
Patent
active
056374607
ABSTRACT:
A method of preparing (e.g., priming) a surface for attachment of a target molecule to the surface. The method provides a multifunctional reagent having multiple photoreactive groups. The groups can be activated in order to covalently bind one or more of them to the surface in such a manner that one or more will remain unbound. The unbound groups are then capable of reverting to their activatable state, whereupon they can again be activated in order to bind a target molecule having abstractable hydrogen atoms.
REFERENCES:
patent: 3616229 (1971-10-01), Wildi et al.
patent: 3959078 (1976-05-01), Guire
patent: 4722906 (1988-02-01), Guire
patent: 4973493 (1990-11-01), Guire
patent: 4979959 (1990-12-01), Guire
patent: 5002582 (1991-03-01), Guire et al.
patent: 5258041 (1993-11-01), Guire et al.
patent: 5414075 (1995-05-01), Swan et al.
patent: 5512329 (1996-04-01), Guire et al.
Whitten et al, (1981), "General Chemistry", Saunders Publishing, New York, p. 793.
Finar et al, (1975), "Organic Chemistry", Longmans Publishing, London, pp. 25-26.
Hilborn et al, (1989), "Photocrosslinking of EPDM elastomers. photocrosslinkable compositions", Rubber Chem. Technol. 62(4):592-608.
Guire, (1976), "Photochemical immobilization of enzymes and other biochemicals" Methods Enzymol. 44:280-288.
Crivello et al, (1993), "Propenyl etheres. I. The synthesis of propenyl ether monomers", J. Polymer Science 31:1473-1482.
Yamamoto et al, (1984), "Restricted rotation involving the tetrahedral carbin. LV. Differential effects of the peri-substituents on the rotational barriers in 9-ethyl, 9-allyl, and 9-benzyltriptycenes", Bull. Chem. Soc. Jpn. 57:2219-2223.
Jensen et al, (1991), "Effect of chemical structure of allyl ethers on polymerization and properties of multifunctional acrylate systems", J. App. Polymer Science 42:2681-2689.
Shimazawa et al, (1991), "Fluorescent and photoaffinity labeling probes for retinoic acid receptors", Biochem. Biophys. Res. Comm. 179(1):259-265.
Jemmerson, R., "Antigenicity and native structure of globular proteins: Low frequency of peptide reactive antibodies", Proc. Nat. Acad. Sci. USA, 84:9180-9184, 1987.
Jemmerson, R., "Multiple overlapping epitopes in the three antigenic regions of horse cytochrome c," J. Immunol. 138:213-219, 1987.
Jentoft, N. and D. Dearborn, "Labeling of proteins by reductive methylation using sodium cyanoborohydride," J. of Biol. Chem. 254:4359-4365 (1979).
Kroschwitz, "Plastics," Concise Encyclopedia of Polymer Science and Engineering, ed., John Wiley and Sons, 462-464, 1990.
Stevens, F.J., "Considerations of the interpretation of the specificity of monoclonal antibodies determined in solid-phase immunoassays," in Immunochemistry of Solid-Phase Immunoassay, J.E. Butler, ed., CRC Press, 233-242, 1991.
Cazaux, et al., "A barum selective macrocyclic tetralartamin with dimethyleneoxy moieties," Tetrahedron Letters 30: 1369-1372 (1989).
Desai, N.P., et al., "Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials," Biomaterials, Mar. 1991, vol. 12, No. 2, pp. 144-153.
Reich, S., et al., "Intraocular-lens-endothelial interface: adhesive force measurements", J. Biomed Mater Res, Sep. 1984, vol. 18, No. 7, pp. 737-744.
Yamamoto, et al., "Restricted internal rotation of a t-butyl group bonded to an aromatic ring," Tetrahedron Letters 27: 49-50 (1986).
Hastings Charles A.
Swan Dale G.
BSI Corporation
Elliott George C.
Fredman Jeffrey
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