Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1994-03-14
1999-10-26
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 4351723, 435220, 435222, 43525231, 4353201, 510300, 536 232, 935 14, 935 29, 935 74, C12N 952, C12N 956, C12N 1575
Patent
active
059726822
ABSTRACT:
Novel carbonyl hydrolase mutants derived from the amino acid sequence of naturally-occurring or recombinant non-human carbonyl hydrolases and DNA sequences encoding the same. The mutant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant carbonyl hydrolase to encode the substitution, insertion or deletion of one or more amino acids in the amino acid sequence of a precursor carbonyl hydrolase. Such mutants have one or more properties which are different than the same property of the precursor hydrolase.
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Bott Richard Ray
Caldwell Robert Mark
Cunningham Brian C.
Estell David Aaron
Power Scott Douglas
Genencor International Inc.
Moore William W.
Silva Robin M.
Trecartin Richard F.
Wax Robert A.
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