Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-08
1995-07-04
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514313, A61K 3144
Patent
active
054300398
ABSTRACT:
A method for inhibiting neuronal cell death in a mammal resulting from a disorder of the central or peripheral nervous system including administering to the mammal a neuronal cell death inhibitng amount of a preparation including any of mepacrine, chloroquine, or hydroxychloroquine, the preparation being essentially free of colchicine.
REFERENCES:
patent: 3830918 (1974-08-01), Molnar et al.
patent: 4840972 (1989-06-01), Effland et al.
Rosner et al., Therapie, XXII:345-354, 1967, "Influence de La chloroquine et de L'hydroxychloroquine sur L'evolution des troubles moteurs post-ischemiques," with attached translation.
Rosner et al., "Therapie, XXII:355-360, 1967, Hydroxychloroquine et resistance corticale e L'anoxie asphyxique," with attached translation.
Larsen et al., Therapie, 33:651-660, 1978, "Modele d'ischemie cerebrale experimentale par microspheres chez le Rat Etude de l'effet de deux extraits de Ginkgo biloba et du naftidrofuryl," with attached translation.
Faden et al., Science, 244:798-800 (1989).
Choi et al., Annual Rev. Of Neuros., 13:171-182 (1990).
Hostetler and Jellison, Mol. Cell. Biochem., 88:77-82 (1989).
Lazarewicz et al., Neuropharmacol., 27:765-769 (1988).
Otamiri and Tagesson, Am. J. Surg., 157:562-565 (1989).
Otani et al., Am. J. Physiol., 257:H252-H258 (1989).
Giulian and Robertson, Ann. Neurol., 27:33-42 (1990).
Murphy et al., FASEB J, 4:1624-1633 (1990).
Badalamente et al., J. of Hand Surgery, 11:337-340 (1986).
Iizuka et al., J. of Neurosurgery, 65:92-98 (1986).
Giulian et al., J. of Neurosci, 9:4416-4429 (1989).
Siman et al., J. of Neurosci., 9:1579-1590 (1989).
Matsuzawa et al., J. Biol. Chem., 255:5190-5194 (1980).
Siesjo (1981), J. Cereb. Blood Flow Metabol., 1:155-185 (1981).
Yawo and Kuno, Science, 222:1351-1353 (1983).
Au et al., J. Cell Biochem, 27:449-453 (1985).
Barbour et al., Nature, 342:918-920 (1989).
DeGeorge et al., J. Neurosci. Res., 21:323-332 (1988).
Reuter, Nature, 301:569-574 (1983).
Goldschmidt et al., Proc. Natl. Acad. Sci. 77:3047-3051, (1980).
Chien et al., The J. of Biol. Chem. 253:4809-4817, (1978).
Norris et al. 1986, British Medical J, vol. 292 pp. 21-23.
Jastremski et al. 1989, JAMA, vol. 262(24) pp. 3427-3430.
Jun et al. CA 68:113285u 1968.
Rosner et al. CA 66:114464x 1967.
Larsen et al. CA 90:115360t 1979.
Lewis Michael E.
Roberts-Lewis Jill M.
Burgoon, Jr. Richard P.
Cephalon Inc.
Cintins Marianne M.
Travers Russell
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