Substituted 1H-1,2,4-triazoles

Details Substituted 1H-1,2,4-triazoles Substituted 1H-1,2,4-triazoles

1980-12-02

1982-05-11

Rollins, Alton D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546276, 424250, 424263, A61K 3144, A61K 31495, C07D40104, C07D40304

Patent

active

043294634

ABSTRACT:
This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted 1-phenyl-1H-1,2,4-triazoles and/or the pharmacologically acceptable acid-addition salts thereof.

REFERENCES:
patent: 2888461 (1959-05-01), Klingsberg
patent: 3489761 (1970-01-01), Kauer
patent: 4038405 (1977-07-01), Evans et al.
patent: 4097599 (1978-06-01), Evans et al.
patent: 4151169 (1979-04-01), Sale et al.
patent: 4256887 (1981-03-01), Novello et al.
Jackson et al., Chemical Abstracts, vol. 45, columns 6699-6700 (1951).

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