Method of producing .alpha..sub.2 -adrenergic receptor agonist a

Details Method of producing .alpha..sub.2 -adrenergic receptor agonist a Method of producing .alpha..sub.2 -adrenergic receptor agonist a

1984-03-19

1985-03-19

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

564387, A61K 31135, C07C 9142

Patent

active

045059322

ABSTRACT:
A method of producing .alpha..sub.2 -adrenergic receptor agonist activity by contacting an .alpha..sub.2 -adrenergic receptor with an effective amount of a compound of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are independently selected from hydrogen or loweralkyl of 1 or 2 carbon atoms, or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3419560 (1968-12-01), Bernstein et al.
Chem. Abstracts, 98:10712f (1982).
Heinsimer et al., "Adrenergic Receptors: Biochemistry, Regulation, Molecular Mechanism, and Clinical Implications", J. Lab. Clin. Med. 100(5): 641-658 (1982).

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