Cyclobutanone antibacterials

Details Cyclobutanone antibacterials Cyclobutanone antibacterials

1982-04-15

1985-03-19

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Acyclic nitrogen double bonded to acyclic nitrogen, acyclic...

2604297, 260464, 260465D, 549336, 556436, 556465, 560 10, 560 32, 560107, 560115, 560116, 560119, 560162, 560256, 514183, 562480, 514519, 514530, C07C14940, A61K 31215

Patent

active

045059055

ABSTRACT:
Certain 7-oxobicyclo[3.2.0] hept-2-en-2-carboxylic acids, esters, and salts thereof useful as antibacterial agents or as intermediates for antibacterial agents, and methods for making and using them.

REFERENCES:
patent: 4216172 (1980-08-01), Heine
Reid, "Organic Chemistry of Bivalent Sulfur", vol. II, pp. 42-46, (1960).
Hoover and Dunn, "The .beta.-Lactam Antibiotics", in Burger's Medicinal Chemistry (Wolff, Ed.), 4th Ed., Part II, Wiley, New York, 1979, pp. 83 to 172.
Gordon et al., in Tetrahedron Letters, 22 (20), 1871 to 1874, (1981).
Meth-Cohn et al., in "Carbocyclic Analogues of Penicillin", J. Chem. Soc., Chem. Commun., pp. 90 to 92, 1982.

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