Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro a

Details Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro a Synthesis of 4-amino-1,2-hydrocarbyl pyrazolidines via 4-nitro a

1981-06-11

1982-11-09

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23104

Patent

active

043585990

ABSTRACT:
4-Nitro-1,2-hydrocarbyl pyrazolidines are prepared by a novel route from 1,2-disubstituted hydrazines and 1,3-di-(secondary amino)-2-nitropropanes and reduced to the corresponding 4-amino-1,2-hydrocarbyl pyrazolidines, which latter compounds are intermediates in the preparation of certain pharmaceutical benzamides.
The novel 4-nitro-1,2-hydrocarbyl pyrazolidines have the formula: ##STR1## wherein R.sup.1 and R.sup.2 are selected from loweralkyl, lowercycloalkyl or phenyl-loweralkyl and may be the same or different.

REFERENCES:
patent: 4207327 (1980-06-01), Lunsford et al.
Luttringhaus et al., Chem. Abst. 1958, vol. 52, p. 9080b.

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