Novel polyvalent virus vaccine against rabies and canine distemp

Drug – bio-affecting and body treating compositions – Lymphokine

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435235, 435239, A61K 39175, A61K 39205

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043584381

ABSTRACT:
A polyvalent virus vaccine for immunization of warm-blooded animals comprising a mixture of a rabies virus, preferably rabies strain No. 675 deposited in the Czechoslovak National Collection of Type Cultures of the Institute of Hygiene and Epidemiology in Prague under No. CNCTC No. A 04/77, and a canine distemper virus, said mixture being substantially free of material emanating from more than one type of tissue cell used to propagate the viruses and a process for its preparation by infecting a suitable single cell system with a rabies virus strain, propagating the rabies virus, infecting the cell system with at least one canine distemper virus, propagating the viruses and separating the polyvalent vaccine from the propagation product.

REFERENCES:
patent: 2908614 (1959-10-01), Muggleton et al.
patent: 3155589 (1964-11-01), Slater
patent: 3228840 (1966-01-01), MacPherson et al.
patent: 3418210 (1968-12-01), Sanders
patent: 3632741 (1972-01-01), Wittmann et al.
V.B. 46 #1894 (1976); 45 #3131 (1975); 44 #2163 #250 (1974); 42 #2099 (1972);41 #3920 (1971); 35 #2150 (1965); 24 #3438 (1959); 36 #2189 (1966); 27 #479 (1957); 21 #2891 (1951); 43 #5504 (1973) Bijlenga et al.

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