Electrodialysis preparation of purified AHF concentrate

Details Electrodialysis preparation of purified AHF concentrate Electrodialysis preparation of purified AHF concentrate

1981-05-22

1984-03-06

Bleutge, John C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424101, 204180R, C07G 700

Patent

active

044353189

ABSTRACT:
A process is described for the preparation of a novel protein product of a highly purified antihemophlic factor (AHF) concentrate. The product is prepared by use of a semi-permeable membrane apparatus that desalts the plasma to between 45 to 80% of its salt content while constantly maintaining the plasma at substantially its original starting pH level. Under these conditions the AHF portion of the plasma will precipitate.

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Morris C. J. O. R., Separation Methods in Biochemistry 1976, pp. 923-927.
Putnam, Frank W., "The Plasma Proteins" 2nd edition, vol. III, Academic Press New York, 1977, pp. 562-565.

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