Method and apparatus for frequency encoded ultrasound-modulated

Details Method and apparatus for frequency encoded ultrasound-modulated Method and apparatus for frequency encoded ultrasound-modulated

1997-10-22

2000-03-21

Kamm, William E.

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

A61B 500

Patent

active

060412488

ABSTRACT:
An apparatus (10) for frequency encoded ultrasound modulated optical tomography is provided. A function generator (12) produces a frequency sweep signal which is applied to an ultrasonic transducer (20). The ultrasonic transducer (20) produces ultrasonic wave (25) in a turbid medium (21). Coherent light from a laser (22) is passed through turbid medium (21) where it is modulated by the ultrasonic wave (25). A photomultiplier tube (24) detects the light which passes through the turbid medium (21). The signal from the photomultiplier tube (24) is fed to an oscilloscope (30) and then to a computer (32) where differences in light intensity at different frequencies can determine the location of objects in the turbid medium (21).

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Fay A. Marks, et al., "A Comprehensive Approach to Breast Cancer Detection Using Light: Photon Localization by Ultrasound Modulation and Tissue Characterization by Spectral Discrimination", SPIE, vol. 1888, 1993, pp. 500-510.
PCT Search Report dated Sep. 1, 1998.
Lihong Wang, et al., "Ultrasound-Modulated Optical Tomography of Dense Turbid Media", SPIE, vol. 2776, pp. 91-102.
Lihong Wang, et al., "Continuous-Wave Ultrasonic Modulation of Scattered Laser Light to Image Objects in Turbid Media", Optical Society of America 1995, pp. 629-631.

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