Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1975-05-08
1977-01-18
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424230, 424231, A61K 3160, A61K 3578
Patent
active
040039994
ABSTRACT:
A novel coprecipitate of aspirin and tea is described. The coprecipitate is prepared by acidification of a solution of aspirin and tea. In vivo pharmacological evaluation of the coprecipitate shows that the therapeutic activity of aspirin has been retained and the side effects commonly associated with aspirin such as irritation of the gastric mucosa, bleeding and ulceration have been markedly reduced.
REFERENCES:
patent: 1486373 (1924-03-01), Gerngross et al.
Journal of the Amer. Pharm. Assoc., vol. 42, pp. 138-145; vol. 43, pp. 527-530 (1953 & 1954).
The Dispensatory of the U.S.A., 24th Ed. (1947), pp. 16-19, 1204-1207 & 1624-1624.
Husa's "Pharmaceutical Dispensing", 5th Ed., (1959), pp. 427-431 & 460-463.
Chem. Abst., vol. 61-14475n, vol. 65-11146a, vol. 65-4263g, vol. 59-6909e.
Bell Louis Gary
Lybrand Robert Archie
A. H. Robins Company Incorporated
Friedman Stanley J.
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