N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subt

Details N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subt N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subt

1996-02-28

1998-01-20

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544295, 544349, 544357, 544363, 544364, 544376, 5462841, 564375, C07D40512, C07D40100, C07D24102, C07D20900

Patent

active

057102740

ABSTRACT:
Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4 are the same or different and represent hydrogen, C.sub.1 -C.sub.6 alkyl, halogen, hydroxy, amino, cyano, nitro, trifluoromethyl, trifluoromethoxy, C.sub.1 -C.sub.6 alkoxy, --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1, or 2; or

REFERENCES:
patent: 3867409 (1975-02-01), Albrecht et al.
patent: 3903116 (1975-09-01), Albrecht et al.
patent: 5395835 (1995-03-01), Glase et al.
Murray et al., (1995), "A Novel Series of Arylpiperazines with High Affinity and Selectivity for the Dopamine D.sub.3 Receptor," Bioorg, Med. Chem. Let., vol. 5, No. 3, pp. 219-222.

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