Phenyl heterocycles as COX-2 inhibitors

Details Phenyl heterocycles as COX-2 inhibitors Phenyl heterocycles as COX-2 inhibitors

1996-08-16

1998-01-20

Owens, Amelia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514424, 514425, 514427, 548413, 548543, 548545, 548546, 548561, 548562, A61K 31675, C07F 902

Patent

active

057101400

ABSTRACT:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

REFERENCES:
patent: 3743656 (1973-07-01), Brown et al.
patent: 4477463 (1984-10-01), Cherkofsky
patent: 4652582 (1987-03-01), Wilkerson
patent: 5196532 (1993-03-01), Wuest et al.
Wilkerson, WW et al Anti Inflammatory 4,5-Diarylpyrodes: Synthesis and QSAR: CA 128:207906 S Apr. 1994.
O'Banion, et al., Proc. Natl. Acad. Sci, USA, vol. 89, pp. 4888-4892 (1992).
Lombardino, et al., Arzneim-Forsch. (Drug Res.), vol. 25, NR. 10, pp. 1629-1635 (1975).
Lombardino, Nonsteroidal Antinflammatory Drugs, pp. 114-130 (1985).

Affiliated with

Also associated with

Rating

Phenyl heterocycles as COX-2 inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenyl heterocycles as COX-2 inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenyl heterocycles as COX-2 inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-725454