Malignancy diagnostic method

Details Malignancy diagnostic method Malignancy diagnostic method

1974-07-08

1977-07-26

Monacell, A. Louis

Textiles: fiber preparation

195 17, C12K 900

Patent

active

040381455

ABSTRACT:
The mixed lymphocyte reaction in tissue culture is used to detect the tumor induced autoimmune reaction which has been found to be characteristic of lymphoid malignancies. Lymphocytes from blood, spleen, and lymph nodes are employed in combinations of two. A mixed lymphocyte reaction from any one of the three possible combinations is indicative of the presence of a lymphoid malignancy.

REFERENCES:
gazit et al., "Mixed Leukocyte Culture with Mouse Spleen Cells in a Serum-Free Medium", Proc. Soc. Exptl. Biol & Med. 140 (1972), pp. 750-754.
Martin et al., "Derepression of Alloantigens in Malignancy", Brit. J. Cancer 28, Suppl. I, (1973), pp. 48-61.
Devlin et al., "Inhibition of Cellular Immune Reactions by Cyclophosphamide Analogues Ifosfamide and Trofosfamide", Proc. Soc. Exptl. Biol & Med. 145 (1974), pp. 389-391.

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