Pharmaceutical component-mixing delivery assembly

Details Pharmaceutical component-mixing delivery assembly Pharmaceutical component-mixing delivery assembly

1992-05-04

1994-01-25

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604191, 604201, 604209, 604232, A61M 3700

Patent

active

052811980

ABSTRACT:
A pharmaceutical component-mixing syringe assembly (2) is particularly suited for packaging, reconstituting and dispensing a series of equal doses of a multiple component pharmaceutical, such as human growth hormone reconstituted from a diluent component (128) and a lyophilized component (34). The pharmaceutical components are contained within first and second cartridges (10, 36) of the type having a movable piston (12, 40). The second cartridge is forced into the interior of the first cartridge causing a spike assembly (132) between the two to fluidly couple the two cartridges and drive the piston of the first cartridge into the first cartridge causing the contents of the first cartridge to be driven into the second cartridge, thereby mixing. A reciprocating ratchet plunger (104) is used to drive the second piston. The distance the ratchet plunger moves, and thus the dose, is determined by the position of a user-inaccessible dosing key stop (116) along the length of the ratchet plunger.

REFERENCES:
patent: 4055177 (1977-10-01), Cohen
patent: 4693706 (1987-09-01), Ennis, III
patent: 4755169 (1988-07-01), Sarnoff et al.
patent: 4886495 (1989-12-01), Reynolds
patent: 5041088 (1991-08-01), Ritson et al.
patent: 5092843 (1992-03-01), Monroe et al.
patent: 5114411 (1992-05-01), Haber et al.

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