Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1995-05-22
1998-01-20
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241391, 435 74, 5303879, 53038822, 5303873, 5303911, 5303913, A61K 39395, C07K 1628
Patent
active
057098581
ABSTRACT:
The protein tyrosine kinase receptors, designated Rse and HPTK6, have been purified from human and/or murine cell tissues. Rse and HPTK6 have been cloned from a cDNA library of a human liver carcinoma cell line (i.e., Hep 3B) using PCR amplification. Provided herein are nucleic acid sequences encoding Rse and HPTK6 useful as diagnostics and in the recombinant preparation of Rse and HPTK6. Rse and HPTK6 are used in the preparation and purification of antibodies thereto and in diagnostic assays.
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Godowski Paul J.
Mark Melanie R.
Scadden David T.
Cech Emma
Chan Christina Y.
Genentech Inc.
Lee Wendy M.
New England Deaconess Hosp.
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